IN VITRO ANTIPLASMODIAL AND CYTOTOXIC ACTIVITIES OF A SUNGKAI (PERONEMA CANESCENS) LEAF EXTRACT
نویسندگان
چکیده
منابع مشابه
Antiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice
Objective: Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malari a infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. Materials and Methods: The active principles of the dried leaf were extracted with ethanol. For quality validation, ch...
متن کاملIn vitro antiplasmodial, antiamoebic, and cytotoxic activities of a series of bisbenzylisoquinoline alkaloids.
Twenty-four bisbenzylisoquinoline alkaloids were screened for antiplasmoidal, antiamoebic, and cytotoxic activities by use of in vitro microtests. Eight of the alkaloids had antiplasmodial activity, with a 50% inhibitory concentration (IC50) of less than 1 microM against a multidrug-resistant strain of Plasmodium falciparum (chloroquine had an IC50 of 0.2 microM). The three alkaloids most activ...
متن کاملAntiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice
OBJECTIVE Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malaria infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. MATERIALS AND METHODS The active principles of the dried leaf were extracted with ethanol. For quality validation, chemi...
متن کاملantiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of vernonia amygdalina del. leaf in swiss mice
objective: vernonia amygdalina (v. amygdalina) leaf is locally employed in the southern region of nigeria in the treatment of malari a infection. this study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of v. amygdalina leaf. materials and methods: the active principles of the dried leaf were extracted with ethanol. for quality validation, ch...
متن کاملAntiplasmodial, Cytotoxic and Acute Toxicity Activities of Vernonia lasiopus
Background: Malaria continues to cause heavy morbidity and mortality and it is the fifth leading cause of death globally. The disease causes over one million deaths annually and affects many more, particularly due to increasing multi-drug resistant strains of Plasmodium falciparum. Sustained investigations in both curative and prophylactic interventions have supported the ethno-pharmacological ...
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ژورنال
عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Sciences
سال: 2018
ISSN: 0975-1491
DOI: 10.22159/ijpps.2018v10i10.25124